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| Catalog Number | Size | Price |
|---|---|---|
| LS-G146-5 | 5 µg | $268 |
| LS-G146-25 | 25 µg | $349 |
Human TLR3 Protein (Recombinant) - LS-G146
Human TLR3 Protein (Recombinant) - LS-G146
Description:
TLR3 Protein LS-G146 is a Recombinant Human TLR3 produced in HEK 293 Cells. It is biologically active and is low in endotoxin; Less than 0.1 ng/µg of protein (less than 1EU/µg). For Research Use Only
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
TLR3 Protein LS-G146 is a Recombinant Human TLR3 produced in HEK 293 Cells. It is biologically active and is low in endotoxin; Less than 0.1 ng/µg of protein (less than 1EU/µg). For Research Use Only
Specifications
Type
Recombinant Protein
Target
TLR3
Synonyms
TLR3 | CD283 | Toll-like receptor 3 | CD283 antigen | IIAE2
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Predicted Molecular Weight
77.4 kDa
AA Sequence
STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDSAPFEL
Expression System
HEK 293 Cells
Source Species
Human
Purification
Greater than 95% by SDS-PAGE and HPLC
Bio-Activity
Determined by its ability to neutralize Poly I:C induced NF-kappaB signaling in HT-29 cells stably transfected with NF-kappaB-luc. The ED50 for this effect is 5-10 ug/ml.
Endotoxin
Less than 0.1 ng/µg of protein (less than 1EU/µg).
Presentation
Filtered and lyophilized from a solution containing 20mM potassium phosphate, pH 7.5.
Reconstitution
Centrifuge the vial before opening. Reconstitute in water to 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week.
Storage
If lyophilized, can be stored for 1 month at room temperature, 3 months at 4°C, or through the expiration date at -20°C to -80°C. Once reconstituted per the supplied instructions, can be stored for 3 months at -20°C to -80°C, or for 1 week at 2°C to 8°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/23/2024
Date Requested: 11/23/2024
