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| Catalog Number | Size | Price |
|---|---|---|
| LS-G47684-5 | 5 µg | $255 |
| LS-G47684-100 | 100 µg | $570 |
| LS-G47684-1 | 1 mg | $2,975 |
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Human IL17 Protein (Recombinant) (Met1-Ala155) - LS-G47684
Human IL17 Protein (Recombinant) (Met1-Ala155) - LS-G47684
Description:
IL17 Protein LS-G47684 is a Recombinant Human IL17 produced in CHO Cells Met1-Ala155. It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
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(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
IL17 Protein LS-G47684 is a Recombinant Human IL17 produced in CHO Cells Met1-Ala155. It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
IL17
Synonyms
IL17
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Applications
- Binding
- ELISA
- Functional Assay
- Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Region
Met1-Ala155
Predicted Molecular Weight
The recombinant human IL17A consists of 132 amino acids and predicts a molecular mass of 15.1 kDa. It migrates as an approximately 16, 19, and 20 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
Expression System
CHO Cells
Source Species
Hamster-Chinese
Purification
(16.9+21.7+50.1) % as determined by SDS-PAGE
Bio-Activity
Measured by its binding ability in a functional ELISA. Immobilized human IL17A at 10 µg/ml (100 µl/well) can bind human IL17Ra, The EC50 of human IL17Ra is 20.0-48.0 ng/ml. Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells in the presense of 20ng/mL TNFa. The ED50 for this effect is 0.2-1ng/mL.
Endotoxin
Less than 1.0 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Reconstitution
Please refer to included instructions for detailed information.
Storage
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
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Functional Assay
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells in the presense of 20ng/mL TNFa. The ED50 for this effect is 0.2-1ng/mL.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Functional Assay
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells in the presense of 20ng/mL TNFa. The ED50 for this effect is 0.2-1ng/mL.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Functional Assay
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells in the presense of 20ng/mL TNFa. The ED50 for this effect is 0.2-1ng/mL.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Functional Assay
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells in the presense of 20ng/mL TNFa. The ED50 for this effect is 0.2-1ng/mL.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
