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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137596-10 | 10 µg (0.2 mg/ml) | $272 |
| LS-G137596-25 | 25 µg (0.2 mg/ml) | $306 |
| LS-G137596-100 | 100 µg | $436 |
Human ICOS / CD278 Protein (Recombinant) - LS-G137596
Human ICOS / CD278 Protein (Recombinant) - LS-G137596
Description:
ICOS / CD278 Protein LS-G137596 is a Recombinant Human ICOS / CD278 produced in CHO Cells. It is low in endotoxin; Less than 0.1 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
ICOS / CD278 Protein LS-G137596 is a Recombinant Human ICOS / CD278 produced in CHO Cells. It is low in endotoxin; Less than 0.1 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
ICOS / CD278
Synonyms
ICOS | AILIM | CD278 | CVID1 | Inducible costimulator | Inducible T-cell co-stimulator | CD278 antigen | Inducible T-cell costimulator
Species
Human
Modifications
Carrier-free
Conjugations
Unconjugated
Predicted Molecular Weight
The 359 amino acid recombinant protein with a C-terminal human IgG1 Fc tag has a predicted molecular mass of approximately 44 kD. The protein migrates above 60 kD in SDS-PAGE in DTT-reducing condition and above 120 kD in non-reducing condition. The N-term
Expression System
CHO Cells
Source Species
Hamster-Chinese
Purification
Greater than 95% by SDS-PAGE
Usage Summary
Stock solutions should be prepared at no less than 10 µg/mL in sterile buffer (PBS, HPBS, DPBS, and EBSS) containing carrier protein such as 1% BSA or HSA.
Bio-Activity
Immobilized human ICOS-Fc Chimera at 1 µg/mL (100 µL/well) can bind recombinant human B7-H2-Fc in a dose dependent manner with a Kd < 5 nM.
Endotoxin
Less than 0.1 EU/µg protein (determined by LAL method).
Presentation
0.22 µm filtered protein solution in PBS
Storage
Store unopened at 2°C to 8°C for up to 3 months, at -20°C for up to 6 months, or at -70°C for up to 1 year. Store diluted at 2°C to 8°C for up to 1 month, or at -20°to -70°C for up to 3 months. Avoid freeze/thaw cycles. For maximum results, quick spin vial prior to opening.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ICOS / CD278
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Functional Assay
Recombinant human ICOS-Fc Chimera is able to bind recombinant human B7-H2-Fc protein in a dose dependent manner. The Kd value of this binding is <5 nM.
Functional Assay
Recombinant human ICOS-Fc Chimera is able to bind recombinant human B7-H2-Fc protein in a dose dependent manner. The Kd value of this binding is <5 nM.
Functional Assay
Recombinant human ICOS-Fc Chimera is able to bind recombinant human B7-H2-Fc protein in a dose dependent manner. The Kd value of this binding is <5 nM.
Functional Assay
Recombinant human ICOS-Fc Chimera is able to bind recombinant human B7-H2-Fc protein in a dose dependent manner. The Kd value of this binding is <5 nM.
Popular ICOS / CD278 Proteins
Source:
E. coli
Tag:
His-GST
Source:
Hamster-Chinese
Tag:
Human IgG1 Fc
Source:
Hamster-Chinese
Tag:
Mouse IgG2 Fc
Source:
Human
Tag:
6His, C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 6/30/2024
Date Requested: 6/30/2024
