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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137009-20 | 20 µg | $405 |
| LS-G137009-100 | 100 µg | $598 |
| LS-G137009-1 | 1 mg | $1,679 |
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Human EPHA2 / EPH Receptor A2 Protein (Recombinant 10His, N-terminus + Myc, C-terminus) - LS-G137009
Human EPHA2 / EPH Receptor A2 Protein (Recombinant 10His, N-terminus + Myc, C-terminus) - LS-G137009
Description:
EPHA2 / EPH Receptor A2 Protein LS-G137009 is a Recombinant Human EPHA2 / EPH Receptor A2 produced in E. coli 28-328aa with 10His, N-terminus + Myc, C-terminus tag(s). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Specifications
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Popular EPHA2 / EPH Receptor A2 Proteins
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Overview
Description:
EPHA2 / EPH Receptor A2 Protein LS-G137009 is a Recombinant Human EPHA2 / EPH Receptor A2 produced in E. coli 28-328aa with 10His, N-terminus + Myc, C-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
EPHA2 / EPH Receptor A2
Synonyms
EPHA2 | CTPA | EPH receptor A2 | Ephrin type-A receptor 2 | Epithelial cell kinase | ECK | Sek-2 | ARCC2 | Soluble EPHA2 variant 1 | CTPP1
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
10His, N-terminus + Myc, C-terminus
Region
28-328aa
Predicted Molecular Weight
38.3 kDa
AA Sequence
EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRP
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 85% by SDS-PAGE
Usage Summary
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris, 50% Glycerol
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About EPHA2 / EPH Receptor A2
Publications (0)
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Mass Cytometry
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Human Ephrin type-A receptor 2(EPHA2),partial could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) EPHA2.
Popular EPHA2 / EPH Receptor A2 Proteins
Source:
Human
Tag:
6His, C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 7/27/2024
Date Requested: 7/27/2024
