Target
BTLA / CD272
Synonyms
BTLA | BTLA1 | B and T lymphocyte associated | CD272 | B and T lymphocyte attenuator | B- and T-lymphocyte attenuator | CD272 antigen
Modifications
Unmodified.
Also available
Preservative Free.
Conjugations
Unconjugated
Region
muCD8 apha signal peptide residual amino acids+ linker.
Predicted Molecular Weight
43.0 kDa
AA Sequence
ipyldiwnihgkescdvqlyikrqsehsilagdpfelecpvkycanrphvtwcklngttcvkledrqtswkeeknisffilhfepvlpndngsyrcsanfqsnlieshsttlyvtdvksaserpskdemasrp
Expression System
CHO Cells
Source Species
Hamster-Chinese
Usage Summary
A soluble fusion protein consisting of the muCD8 apha signal peptide residual amino acids+ linker: (1)kpqapelrgs(10), CD272 mature EC: (11)ipyldiwnihgkescdvqlyikrqsehsilagdpfelecpvkycanrphvtwcklngttcvkledrqtswkeeknisffilhfepvlpndngsyrcsanfqsnlieshsttlyvtdvksaserpskdemasrp(143), Linker + Murine IgG2a Hinge + Fc: (144)gteprgptikpcppckcpapnllggpsvfifppkikdvlmislspivtcvvvdvseddpdvqiswfvnnvevhtaqtqthredynstlrvvsalpiqhqdwmsgkefkckvnnkdlpapiertiskpkgsvrapqvyvlpppeeemtkkqvtltcmvtdfmpediyvewtnngktelnykntepvldsdgsyfmysklrvekknwvernsyscsvvheglhnhhttksfsrtpg(378). Predicted monomeric (non glycosylated) molecular weight: 43.0 kd. The molecule is dimeric and runs at ~100 kd in SDS-PAGE under native conditions, and ~50kd reduced. N-terminal sequence was as predicted: KPQAP. Recombinant protein was detectable at 10 ng/ml in EIA using Goat-anti-Mouse as a capture antibody and recombinant CD270(HVEM)-muIg/Biotin followed by SA/HRP as detection reagents.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl, 0.5 mg/ml Gentamicin Sulfate
Storage
Store at 2°C to 5°C for up to 6 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee