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Vector Laboratories, Inc.
6737 Mowry Ave
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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137189-20 | 20 µg | $405 |
| LS-G137189-100 | 100 µg | $598 |
| LS-G137189-1 | 1 mg | $1,679 |
Alpha-conotoxin(Conus vexillum) Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (Full Length) - LS-G137189
Alpha-conotoxin(Conus vexillum) Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (Full Length) - LS-G137189
Description:
Alpha-conotoxin(Conus vexillum) Protein LS-G137189 is a Recombinant Alpha-conotoxin(Conus vexillum) produced in E. coli 1-47aa with 10His-SUMO, N-terminus + Myc, C-terminus tag(s). For Research Use Only
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
Alpha-conotoxin(Conus vexillum) Protein LS-G137189 is a Recombinant Alpha-conotoxin(Conus vexillum) produced in E. coli 1-47aa with 10His-SUMO, N-terminus + Myc, C-terminus tag(s). For Research Use Only
Specifications
Type
Recombinant Protein
Target
Alpha-conotoxin(Conus vexillum)
Species
Conus vexillum
Modifications
Unmodified
Conjugations
Unconjugated
Tag
10His-SUMO, N-terminus + Myc, C-terminus
Region
1-47aa
Predicted Molecular Weight
25.3 kDa
AA Sequence
DLRQCTRNAPGSTWGRCCLNPMCGNFCCPRSGCTCAYNWRRGIYCSC
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 85% by SDS-PAGE
Usage Summary
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7/CHRNA7 and alpha-3-beta-2/CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2/CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA.
Bio-Activity
Not Tested
Endotoxin
Not Tested
Presentation
Lyophilized from Tris, 50% Glycerol
Storage
Store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
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Images
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/22/2024
Date Requested: 12/22/2024
