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PathPlusTM VIL1 / Villin Antibodies
Villin (VIL1) is a tissue specific actin modifying protein associated with actin filaments in microvilli and the terminal web of epithelial cells. It is involved in regulating actin dynamics, cell morphology, the epithelial-mesenchymal transition, cell migration, and cell survival. Deregulation of this gene may contribute to tumorigenesis. Loss of expression of villin is seen in poorly differentiated colorectal carcinomas, particularly in microsatellite-unstable (MSI) tumors, and is linked to poor survival. In normal tissues, it is expressed on luminal membranes (microvilli) of the gastrointestinal epithelium, as well as in proximal convoluted tubules of the kidney and gallbladder. VIL1 is positive in pulmonary adenocarcinomas, colon adenocarcinomas, and renal cell carcinomas. References: FEBS Lett 2008 582(14):2128; Patnaik 2016; Arango 2012; Jaudah 2013

3 PathPlusTM Antibodies
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Antibodies (3)
Primary (3)
VIL1 / Villin (3)
Human (3)
IHC (1)
IHC-P (3)
WB (1)
rabbit (1)
mouse (2)
Product Group
PathPlus Cancer (3)
PathPlus Cancer Pathology (3)
IgG (2)
IgG1,k (1)
monoclonal mc (1)
recombinant monoclonal rmc (2)
rVIL1/1325 (1)
VIL1/2310R (1)
Unconjugated (3)
aa179-311 (2)
No (3)
VIL1 / Villin Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
VIL1 / Villin Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
VIL1 / Villin Antibody - Human Smal Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
VIL1 / Villin Mouse anti-Human Recombinant Monoclonal (aa179-311) (rVIL1/1325) Antibody
Human
IHC-P
Unconjugated
100 µg/$485
VIL1 / Villin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
VIL1 / Villin Rabbit anti-Human Recombinant Monoclonal (aa179-311) (VIL1/2310R) Antibody
Human
IHC-P
Unconjugated
100 µg/$525
Viewing 1-3 of 3 product results