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PPY / Pancreatic Polypeptide
pancreatic polypeptide
PPY / Pancreatic Polypeptide belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.
| Gene Name: | pancreatic polypeptide |
| Family/Subfamily: | Pancreatic hormone , not assigned-Pancreatic hormone |
| Synonyms: | PPY, Obinepitide, Pancreatic polypeptide Y, Pancreatic prohormone, PP, Pancreatic polypeptide, Pancreatic hormone |
| Target Sequences: | NM_002722 NP_002713.1 P01298 |
Publications (4)
1
Establishment of an enzyme-linked immunosorbent assay for mouse pancreatic polypeptide clarifies the regulatory mechanism of its secretion from pancreatic ? cells. Daisuke Saito, Yuko Nakagawa, Takashi Sato, Ayako Fukunaka, Ofejiro Blessing Pereye, Nobuhiro Maruyama, Hirotaka Watada, Yoshio Fujitani. PloS one. 2022 August;17:e0269958. [Full Text Article]
[PubMed:35976945]
[PMC:PMC9385059]
2
Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of rats. Chen Y, Hong F, Chen H, Fan RF, Zhang XL, Zhang Y, Zhu JX. Cell and tissue research. 2014 Sep;357:597-606. [Full Text Article]
[PubMed:24825414]
Related Antibodies: LS-B5911.
3
New perspectives of vesicular monoamine transporter 2 chemical characteristics in mammals and its constant expression in type 1 diabetes rat models. Hong F, Liu L, Fan RF, Chen Y, Chen H, Zheng RP, Zhang Y, Gao Y, Zhu JX. Translational research : the journal of laboratory and clinical medicine. 2014 Feb;163:171-82. [Full Text Article]
[PubMed:24161354]
Related Antibodies: LS-B5911.
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(80)
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(14)
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PPY / Pancreatic Polypeptide Goat anti-Human Polyclonal (aa61-73) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
Competitive EIA
96-Well Strip Plate
Rat
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$750
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Competitive EIA
96-Well Strip Plate
Human
37.04 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
Sandwich
96-Well Microplate
Human
46.88 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (2G5D12) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
PPY / Pancreatic Polypeptide Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$508; 100 µg/$860
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
Competitive EIA
96-Well Strip Plate
Rat
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
E. coli
His-GST
39.0 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
PPY / Pancreatic Polypeptide Rabbit anti-Mouse Polyclonal (aa31-97) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PPY / Pancreatic Polypeptide Rabbit anti-Mouse Polyclonal (aa31-97) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
PPY / Pancreatic Polypeptide Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
200 µg/$1,027
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal (aa30-87) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
0.5 ml/$485
Competitive EIA
96-Well Strip Plate
Mouse
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
Sandwich
96-Well Strip Plate
Pig
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
E. coli
His-GST
39.8 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC
Unconjugated
50 µl/$572
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (Amino Acid: 1-95) (2G5D12) Antibody
Human
Flo, WB
Unconjugated
100 µg/$503
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (2C10-C7-H5-C9-G9) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (2C11-F11-F6-G8-E11-G10) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
PPY / Pancreatic Polypeptide Mouse anti-Human Monoclonal (4C1-E11-E10-F2) Antibody
Human
ELISA, WB
Unconjugated
20 µg/$241; 100 µg/$303; 200 µg/$334; 500 µg/$452
PPY / Pancreatic Polypeptide Rabbit anti-Bovine Polyclonal (Concentrated) Antibody
Bovine
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
50 µl/$529
PPY / Pancreatic Polypeptide Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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