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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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PathPlusTM NPY5R Antibodies
NPY5R (Neuropeptide Y receptor type 5) is a receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. It is associated with food intake and could be involved in feeding disorders. In neuroblastoma, copy-number alterations in NPY5R have been observed, and it is overexpressed specifically in chemotherapy-treated tumors and is thought to be involved in a chemoresistant pro-survival loop.
References: Can Res Tumor Biology. 2017. 77 (13). DOI: 10.1158/1538-7445.AM2017-5822; Oncogene. 2015 Jun 11;34(24):3131-43, PMID: 25132261
1 PathPlusTM Antibody
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Antibodies
(1)
Type
Primary
(1)
Target
NPY5R
(1)
Reactivity
Human
(1)
Monkey
(1)
Application
IHC
(1)
IHC-P
(1)
Host
rabbit
(1)
Product Group
GPCR Database Antibodies
(1)
PathPlus Cancer
(1)
Clonality
polyclonal pc
(1)
Format
Unconjugated
(1)
Epitope
Cytoplasmic Domain
(1)
Publications
No
(1)
Cancer
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NPY5R Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$395
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