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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Antibodies to melanoma antigens, such as clones PNL2 and KBA.62, are useful for the identification of melanoma in immunohistochemistry. PNL2 detects a fixative-resistant melanocyte antigent and allows for staining after decalcification or melanin bleaching. It is used to label neoplastic cells in primary melanomas. KBA.62 also detects a melanoma-associated antigen, and reacts strongly with both benign and malignant melanocytic proliferations and is useful for diagnosing primary and metastatic melanoma, including desmoplastic melanoma.
References: Mod Pathol. 2003 May;16(5):481-90, PMID: 12748255; Journal of Clinical Pathology 1995;48:826-831, DOI: 10.1136/jcp.48.9.826; Hum Pathol. 2008 Aug;39(8):1136-42, PMID: 18495211; J Invest Dermatol. 2005 Feb;124(2):412-8, PMID: 15675962