GRB7

growth factor receptor-bound protein 7

Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress.

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Products

Antibodies (52)

Proteins (11)

ELISA Kits (8)

Type

Over-Expression Lysate (5)

Primary (52)

Recombinant (6)

Sandwich (8)

Target

GRB7 (71)

Reactivity

Human (44)

Mouse (22)

Rat (13)

Bat (1)

Chicken (2)

Guinea pig (2)

Hamster (1)

Monkey (2)

Pig (1)

Porcine (1)

Rabbit (1)

Sheep (1)

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Application

IHC (10)

IHC-P (6)

WB (48)

Flo (1)

ELISA (16)

IP (2)

Peptide-ELISA (2)

Host

rabbit (45)

mouse (6)

goat (1)

Product Group

PathPlus Other (1)

Isotype

IgG (21)

IgG1 (2)

IgG2b (2)

IgG2b,l (1)

Clonality

monoclonal mc (5)

polyclonal pc (47)

Clone

3C12 (1)

OTI15E7 (2)

OTI6H2 (2)

Format

12 x 8-Well Microstrips (1)

96-Well Strip Plate (7)

APC (2)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (4)

Carrier-free (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (4)

Unconjugated (28)

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Epitope

aa298-489 (8)

aa66-327 (8)

aa289-318 (7)

aa233-532 (2)

C-Terminus (1)

N-Terminus (1)

aa1-140 (1)

aa1-532 (1)

aa124-141 (1)

aa176-192 (1)

aa25-38 (1)

aa30-100 (1)

aa35-201 (1)

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Publications

No (71)

Sample Type

Plasma (2)

Serum (2)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (5)

Species

Human (8)

Mouse (1)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (1)

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GRB7 Antibody (aa35-201) LS-C178977

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa35-201) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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GRB7 Antibody (aa233-532) LS-C375838

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa233-532) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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GRB7 Antibody (clone 3C12) LS-C197346

Antibody:

GRB7 Mouse anti-Human Monoclonal (3C12) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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GRB7 Antibody (aa1-140) LS-C334219

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa1-140) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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GRB7 Antibody (clone OTI6H2) LS-C800060

Antibody:

GRB7 Mouse anti-Human Monoclonal (OTI6H2) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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GRB7 Antibody (clone OTI6H2, Carrier-free) LS-C791989

Antibody:

GRB7 Mouse anti-Human Monoclonal (Carrier-free) (OTI6H2) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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PathPlus™ GRB7 Antibody LS-A11423

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Antibody:

GRB7 Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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GRB7 Antibody (aa233-532) LS-C375841

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa233-532) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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GRB7 Antibody (aa176-192) LS-C312744

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa176-192) Antibody

Reactivity:

Chicken, Pig, Bat, Guinea pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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GRB7 Antibody (aa124-141) LS-C388507

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa124-141) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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GRB7 Antibody LS-C341816

Antibody:

GRB7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

GRB7 Antibody LS-C665983

Antibody:

GRB7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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GRB7 Antibody LS-C404026

Antibody:

GRB7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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GRB7 Antibody (N-Terminus) LS-C46971

Antibody:

GRB7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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GRB7 Antibody (C-Terminus) LS-C46822

Antibody:

GRB7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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GRB7 Antibody (aa289-318) LS-C321778

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa289-318) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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GRB7 Antibody (aa289-318, Biotin) LS-C235966

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa289-318) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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GRB7 Antibody (aa289-318, FITC) LS-C235968

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa289-318) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

GRB7 Antibody (aa289-318, APC) LS-C235969

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa289-318) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

GRB7 Antibody (aa289-318, PE) LS-C235974

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa289-318) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE

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GRB7 Antibody (clone OTI15E7) LS-C794826

Antibody:

GRB7 Mouse anti-Human Monoclonal (OTI15E7) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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GRB7 Antibody (aa30-100) LS-C813864

Antibody:

GRB7 Rabbit anti-Human Polyclonal (aa30-100) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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GRB7 Antibody LS-C308111

Antibody:

GRB7 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

GRB7 Antibody LS-C778947

Antibody:

GRB7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

100 µg/$357

Select

GRB7 Antibody LS-C806993

Antibody:

GRB7 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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