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PathPlusTM DES / Desmin Antibodies
Desmin (DES) is a subunit of intermediate filaments in muscles that controls sarcomere architecture. Mutations in desmin that result in excess aggregation of the protein throughout the cell are associated with cardiomyopathy and myofibrillar myopathy diseases. In immunohistochemistry, desmin is commonly used as a mesenchymal marker and is useful for confirming myogenic origin of tissues and distinguishing smooth muscle tumors (desmin positive) from GIST (desmin negative). It is also positive in reactive mesothelial cells, skeletal muscle tumors, leiomyomas and rhabdomyosarcomas. References: Biophysical Reviews. 2018 Aug. 10 (4): 983–1006, PMID: 29926427; Biochimica et Biophysica Acta. 2014 Feb. 1838 (2): 700–22, PMID: 23860255; Journal of Structural Biology. 2014 Nov. 148 (2): 137–52, PMID: 15477095; The American Journal of Cardiology. 2013 Feb. 111 (3): 400–5, PMID: 23168288; Genet Med. 2019 May;21(5):1246-1247, PMID: 30262925

4 PathPlusTM Antibodies
☰ Filters
Antibodies (4)
Primary (4)
DES / Desmin (4)
Human (4)
Mouse (1)
Rat (1)
Chicken (1)
Pig (1)
Rabbit (1)
IHC (3)
IHC-Fr (2)
IHC-P (4)
WB (2)
rabbit (1)
mouse (3)
Product Group
PathPlus Cancer (4)
PathPlus Cancer Pathology (4)
IgG (2)
IgG1 (2)
monoclonal mc (3)
recombinant monoclonal rmc (1)
D33 (1)
D9 (1)
DES/2960R (1)
Concentrated (1)
Unconjugated (4)
No (4)
DES / Desmin Antibody - Anti-DES / Desmin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
DES / Desmin Mouse anti-Human Monoclonal (D9) Antibody
Chicken, Rabbit, Mouse, Rat, Pig, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
DES / Desmin Antibody - Anti-DES / Desmin antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Cancer Pathology
Cancer
DES / Desmin Mouse anti-Human Monoclonal (Concentrated) (D33) Antibody
Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
50 µl/$460
DES / Desmin Antibody - Human colon, smooth muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
DES / Desmin Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$460
DES / Desmin Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
DES / Desmin Rabbit anti-Human Recombinant Monoclonal (DES/2960R) Antibody
Human
IHC-P
Unconjugated
100 µg/$525
Viewing 1-4 of 4 product results