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PathPlusTM CTNNB1 / Beta Catenin Antibodies
Beta-Catenin (CTNNB1) is a member of the armadillo family of proteins, and part of the Wnt/beta-catenin signaling pathway. It binds to the cytoplasmic region of the e-cadherin molecule (part of the adherens junction), a complex that is necessary for the creation and maintenance of epithelial layers by regulating cell growth and adhesion, as well as anchoring the actin cytoskeleton. This protein also binds to the APC gene, and mutations in this gene are implicated in colon cancer, papillary thyroid cancer, pilomatrixoma, medulloblastoma, and ovarian cancer. In pathology, CTNNB1 is used to identify desmoid tumors, colorectal cancer, and colon adenomas. It is positive in the membrane of the epithelium of the colon and appendix, weak in endothelial cells, hepatocytes, satellite cells in nerves and follicular dendritic cells in lymph nodes. Staining is membranous in normal colon, and can become nuclear in adenomas and adenocarcinomas. References: Prakash, J Oral Maxillofac Pathol 2015 19(2):230; Luu 2004, Curr Cancer Drug Targets 4(8):653.

8 PathPlusTM Antibodies
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Antibodies (8)
Primary (8)
CTNNB1 / Beta Catenin (8)
Human (7)
Mouse (4)
Rat (2)
Bovine (1)
Hamster (1)
IHC (3)
IHC-Fr (1)
IHC-P (7)
WB (6)
Flo (2)
ICC (1)
IF (3)
IP (2)
SWB (1)
rabbit (5)
mouse (3)
Product Group
PathPlus Cancer (8)
PathPlus Cancer Pathology (8)
IgG (3)
IgG1 (1)
IgG1,k (1)
IgG2a (1)
monoclonal mc (2)
polyclonal pc (4)
recombinant monoclonal rmc (2)
14 (1)
CTNNB1/2030R (1)
EM-22 (1)
rCTNNB1/2173 (1)
Unconjugated (8)
C-Terminus (1)
No (8)
CTNNB1 / Beta Catenin Antibody - Anti-CTNNB1 / Beta Catenin antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
CTNNB1 / Beta Catenin Mouse anti-Human Monoclonal (EM-22) Antibody
Mouse, Hamster, Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
0.05 mg/$460
CTNNB1 / Beta Catenin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CTNNB1 / Beta Catenin Rabbit anti-Human Recombinant Monoclonal (CTNNB1/2030R) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
100 µg/$525
CTNNB1 / Beta Catenin Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CTNNB1 / Beta Catenin Mouse anti-Human Recombinant Monoclonal (rCTNNB1/2173) Antibody
Human
IF, IHC-P, WB
Unconjugated
100 µg/$525
CTNNB1 / Beta Catenin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CTNNB1 / Beta Catenin Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
120 µl/$460
CTNNB1 / Beta Catenin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CTNNB1 / Beta Catenin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC-P, IP, WB
Unconjugated
50 µl/$460
CTNNB1 / Beta Catenin Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CTNNB1 / Beta Catenin Rabbit anti-Human Polyclonal Antibody
Mouse, Bovine, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
CTNNB1 / Beta Catenin Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CTNNB1 / Beta Catenin Mouse anti-Human Monoclonal (14) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.05 ml/$460
CTNNB1 / Beta Catenin Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
Fast Shipping
CTNNB1 / Beta Catenin Rabbit anti-Human Polyclonal Antibody
IHC-P, SWB
Unconjugated
50 µg/$460
Viewing 1-8 of 8 product results