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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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PathPlusTM AIF1 / IBA1 Antibodies
AIF1 (allograft inflammatory factor 1, IBA1) is an actin- and calcium-binding protein that enhances membrane ruffling and RAC activation. It is expressed in microglia in the central nervous system and in macrophages, where it plays a role in RAC signaling, phagocytosis, macrophage activation and function, vascular inflammation. Furthermore, it promotes the proliferation of vascular smooth muscle cells and T-lymphocytes. In immunohistochemistry, AIF1 serves as a marker for microglia and for macrophages. In cancer, it can also be used to differentiate malignant reticuloses (AIF1 positive) from astrocytomas (negative). In normal tissues, AIF1 has cytoplasmic and membranous positivity in immune cells, with particularly high expression in macrophages in the lung. References: J Neurochem. 2004 Feb;88(4):844-56, PMID: 14756805; Mol Med. 2015; 21(1): 233–241, PMID: 25569805; Neuroscience and Behavioral Physiology. March 2016, Volume 46, Issue 3, pp 284–290; J Toxicol Pathol. 2013 Mar; 26(1): 55–60, PMID: 23723569

5 PathPlusTM Antibodies
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Antibodies (5)
Primary (5)
AIF1 / IBA1 (5)
Human (5)
Mouse (4)
Rat (4)
Dog (1)
Horse (1)
Pig (1)
IHC (4)
IHC-P (5)
WB (5)
ELISA (1)
Peptide-ELISA (1)
rabbit (4)
goat (1)
Product Group
PathPlus Neuro (5)
IgG (1)
polyclonal pc (5)
Unconjugated (5)
aa1-147 (1)
aa42-56 (1)
aa85-147 (1)
No (4)
Yes (1)
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
AIF1 / IBA1 Goat anti-Human Polyclonal (aa42-56) Antibody
Dog, Pig, Horse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AIF1 / IBA1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
AIF1 / IBA1 Rabbit anti-Rat Polyclonal (aa1-147) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Neuroscience
AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
AIF1 / IBA1 Rabbit anti-Human Polyclonal (aa85-147) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
AIF1 / IBA1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
Viewing 1-5 of 5 product results