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| Catalog Number | Size | Price |
|---|---|---|
| LS-B6186-50 | 50 µg (0.1 mg/ml) | $460 |
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PathPlus™ Monoclonal Mouse anti‑Human TNFRSF14 / CD270 / HVEM Antibody (clone 2G6‑2C7, IHC, WB) LS‑B6186
PathPlus™ Monoclonal Mouse anti‑Human TNFRSF14 / CD270 / HVEM Antibody (clone 2G6‑2C7, IHC, WB) LS‑B6186
Note: This antibody replaces LS-C133568
Antibody:
TNFRSF14 / CD270 / HVEM Mouse anti-Human Monoclonal (2G6-2C7) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TNFRSF14 / CD270 / HVEM Mouse anti-Human Monoclonal (2G6-2C7) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
CD270 (also called tumor necrosis factor receptor superfamily member 14, TNFRSF14, herpes virus entry mediator A, HVEM) is a cell-surface receptor and member of the TNF-receptor superfamily. It binds four distinct ligands as well as herpes simplex virus and is involved in complex signaling pathways. CD270 is involved in the pathogenesis of various autoimmune, inflammatory, and neoplastic diseases. It is broadly expressed in many tissues as well as B cells, monocytes, and T cells. Mutations are associated with pediatric follicular lymphomas and with poor prognosis in follicular lymphomas.
References: Nat Immunol. 2008;9(2):176-185. doi: 10.1038/ni1554; J Immunol. 2009;183(11):7286-7296. doi: 10.4049/jimmunol.0902490; Nat Rev Immunol. 2006;6(9):671-681. doi: 10.1038/nri1917; Front Immunol. 2019;10:617. doi:10.3389/fimmu.2019.00617; Haematologica 2013 98(8):1237;Cancer Res 2010 70(22):9166
Target
Human TNFRSF14 / CD270 / HVEM
Synonyms
TNFRSF14 | CD270 | CD270 antigen | CD40-like protein | Herpesvirus entry mediator | Herpesvirus entry mediator A | HVEM | LIGHTR | Herpes virus entry mediator A | TR2 | ATAR | HVEA
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Clone
2G6-2C7
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
TNFRSF14 (AAH02794, 38 aa ~ 284 aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human TNFRSF14
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using transfected cell lysates and the recombinant protein used as the immunogen.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TNFRSF14 / CD270 / HVEM
Validation
Anti-TNFRSF14 / CD270 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-TNFRSF14 / CD270 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
PathPlus™ TNFRSF14 / CD270 / HVEM Antibody (clone 2G6-2C7) for IHC, WB/Western, ELISA LS-B6186 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/28/2024
Date Requested: 11/28/2024
