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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2381-50 | 50 µg (0.5 mg/ml) | $485 |
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PathPlus™ Polyclonal Goat anti‑Human S100A4 / FSP1 Antibody (aa80‑C‑term, IHC, WB) LS‑B2381
PathPlus™ Polyclonal Goat anti‑Human S100A4 / FSP1 Antibody (aa80‑C‑term, IHC, WB) LS‑B2381
Note: This antibody replaces LS-C55425
Antibody:
S100A4 / FSP1 Goat anti-Human Polyclonal (aa80-C-term) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Bovine, Dog, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
S100A4 / FSP1 Goat anti-Human Polyclonal (aa80-C-term) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Bovine, Dog, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
S100A4 is a member of the S100 family of calcium-binding proteins that is involved in the regulation of angiogenesis, cell survival, motility and invasion. It is expressed in the nucleus, cytoplasm and extracellular space. It is expressed in a variety of cell types, including fibroblasts, macrophages, lymphocytes, neutrophils, endothelial cells, and smooth muscle. S100A4 also has been implicated in tumor progression and metastasis by stimulating cell motility, stimulating degradation of matrix components and stimulating angiogenesis.
References: Oncotarget 2017 8(42):73219; Am J Pathol 2010 176(2):528
Target
Human S100A4 / FSP1
Synonyms
S100A4 | 42A | 18A2 | Fibroblast-specific protein-1 | FSP1 | MTS1 | PEL98 | Protein Mts1 | Calvasculin | CAPL | Metastasin | p9KA | Protein S100-A4
Host
Goat
Reactivity
Human, Bovine, Dog, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
A synthetic peptide corresponding to residues on the C-Terminus in human S100A4 was used as an immunogen.
Epitope
aa80-C-term
Specificity
Human S100A4 / FSP1.
Applications
- IHC
- IHC - Paraffin (2.5 - 5 µg/ml)
- Western blot (0.05 - 0.2 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:128000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2381 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2381 was determined to be 2.5-5 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About S100A4 / FSP1
Validation
Anti-S100A4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-S100A4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-S100A4 antibody IHC of human uterus, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-S100A4 antibody IHC of human uterus, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
PathPlus™ S100A4 / FSP1 Antibody (aa80-C-term) for IHC, WB/Western LS-B2381 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Retinoic acid synthesis by a population of choroidal stromal cells. Jody A Summers, Elizabeth Martinez Cano, Alexandra Kaser-Eichberger, Falk Schroedl. Experimental eye research. 2020 December;201:108252.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/13/2024
Date Requested: 11/13/2024
