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| Catalog Number | Size | Price |
|---|---|---|
| LS-A412-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human RAIG2 / GPRC5B Antibody (C‑Terminus, IHC) LS‑A412
PathPlus™ Polyclonal Rabbit anti‑Human RAIG2 / GPRC5B Antibody (C‑Terminus, IHC) LS‑A412
Antibody:
RAIG2 / GPRC5B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
RAIG2 / GPRC5B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
GPRC5B is a G protein-coupled receptor induced by retinoids. GPRC5B shows some homology to the metabotropic glutamate receptor-like family of GPCRs. In mice, GPRC5B has been shown to regulate neuronal differentiation in the developing neocortex. Additionally, GPRC5B is expressed in breast cancer cell lines versus absence in normal control cells, and may be an effective biomarker for breast cancer. In immunohistochemistry, GPRC5B has membranous and cytoplasmic positivity throughout the central nervous system, the kidney, reproductive tissues, the breast, gastrointestinal tract, kidney and a few other tissues.
References: Front Pharmacol. 2018 May 22;9:431, PMID: 29872392; Development 2013 140: 4335-4346; doi: 10.1242/dev.099754
Target
Human RAIG2 / GPRC5B
Synonyms
GPRC5B | A-69G12.1 | RAIG2 | RAIG-2
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Predicted
Bovine, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from C-Terminus of human GPRC5B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Orangutan (95%); Panda, Dog, Bovine, Horse, Turkey (90%); Pig, Opossum (85%).
Epitope
C-Terminus
Specificity
Human GPRC5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (2 - 5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About RAIG2 / GPRC5B
Validation
Hodgkin's lymphoma
Hodgkin's lymphoma
Non-Hodgkin's lymphoma
Non-Hodgkin's lymphoma
Anti-GPRC5B antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPRC5B antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Skin, Malignant Melanoma
Skin, Malignant Melanoma
See More About...
LSBio Ratings
PathPlus™ RAIG2 / GPRC5B Antibody (C-Terminus) for IHC LS-A412 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Bovine, Dog, Horse, Pig
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
