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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1922-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human QRFPR / GPR103 Antibody (Cytoplasmic Domain, IHC) LS‑A1922
PathPlus™ Polyclonal Rabbit anti‑Human QRFPR / GPR103 Antibody (Cytoplasmic Domain, IHC) LS‑A1922
Antibody:
QRFPR / GPR103 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
QRFPR / GPR103 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Pyroglutamylated RFamide peptide receptor (QRFPR, GPR103) is a G-protein coupled receptor that binds neuropeptides such as P518 (and the longer form, QRFP) in the brain. It is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels, and it regulates adrenal function via QRFP/P518. In immunohistochemistry, it has membranous and cytoplasmic positivity in the hypothalamus, kidney, thyroid, reproductive tissues, and pancreas and has lower levels of expression in a few other tissues.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human QRFPR / GPR103
Synonyms
QRFPR | AQ27 | G protein-coupled receptor 103 | QRFP receptor | SP9155 | G-protein coupled receptor 103 | GPR103
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from the C-Terminus cytoplasmic domain of human QRFPR / GPR103. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset (95%); Dog (85%); Horse, Rabbit (80%).
Epitope
Cytoplasmic Domain
Specificity
Human QRFPR / GPR103. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About QRFPR / GPR103
Validation
Brain, Hypothalamus, PVN
Brain, Hypothalamus, PVN
Brain, Accessory Nucleus
Brain, Accessory Nucleus
Anti-QRFPR / GPR103 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-QRFPR / GPR103 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ QRFPR / GPR103 Antibody (Cytoplasmic Domain) for IHC LS-A1922 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
Western blot, ELISA
Species:
Human, Bovine, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot
Source:
E. coli
Tag:
His-GST
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
