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| Catalog Number | Size | Price |
|---|---|---|
| LS-B10740-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Monoclonal Mouse anti‑Human PAX5 Antibody (clone 7D3, IHC, WB) LS‑B10740
PathPlus™ Monoclonal Mouse anti‑Human PAX5 Antibody (clone 7D3, IHC, WB) LS‑B10740
Note: This antibody replaces LS-C169109
Antibody:
PAX5 Mouse anti-Human Monoclonal (7D3) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
PAX5 Mouse anti-Human Monoclonal (7D3) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
PAX5 is a paired box family transcription factor involved in B-cell differentiation and in the development of the testis and central nervous system. In normal tissue, PAX5 has specific nuclear expression in pre-B cells and is downregulated in plasma cells. In cancer it is positive in pre B-cell acute lymphoblastic leukemia and classical Hodgkin leukemia (Reed-Sternberg cells), merkel cell carcinomas, small cell carcinomas and high grade neuroendocrine carcinomas. PAX5 is a useful marker for distinguishing lymphoplasmacytic lymphomas (PAX5 positive) from plasmocytomas (negative).
References: Adv Anat Pathol. 2007 Sep;14(5):323-34, PMID: 17717432; Am J Surg Pathol. 2005;29:687, PMID: 15832095; Am J Clin Pathol 2008;129:556, PMID: 18343782, Am J Clin Pathol. 2006;126:798, PMID: 17050077; Am J Surg Pathol 2002;26:1343, PMID: 12360049
Target
Human PAX5
Synonyms
PAX5 | BSAP | Paired box 5 | Paired box protein Pax-5 | Transcription factor PAX 5 | Paired box homeotic gene 5 | PAX-5
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
7D3
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Purified recombinant fragment of human PAX5 (AA: 235-382) expressed in E. Coli.
Specificity
Human
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (1:100 - 1:500)
- ELISA (1:10000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PAX5
Validation
Anti-PAX5 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-PAX5 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
PathPlus™ PAX5 Antibody (clone 7D3) for IHC, WB/Western, ELISA LS-B10740 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
