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Catalog Number Size Price
LS-A233-50 50 µg (1 mg/ml) $460 
OPRM1 / Mu Opioid Receptor Antibody - Brain, Putamen
OPRM1 / Mu Opioid Receptor Antibody - Anti-OPRM1 / Mu Opioid Receptor antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
OPRM1 / Mu Opioid Receptor Antibody - Brain, Putamen
OPRM1 / Mu Opioid Receptor Antibody - Anti-OPRM1 / Mu Opioid Receptor antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human OPRM1 / Mu Opioid Receptor Antibody (Extracellular Domain, IHC) LS‑A233

PathPlus™ Polyclonal Rabbit anti‑Human OPRM1 / Mu Opioid Receptor Antibody (Extracellular Domain, IHC) LS‑A233

Antibody:
OPRM1 / Mu Opioid Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-A233-50

Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
OPRM1 / Mu Opioid Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified

Specifications

Description
Opioid receptor, mu 1 (OPRM1, MOR) is a receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. It has inhibitory action and functions to lower cAMP levels. In the brain, it regulates the excitability of neurons, and activation by various agonists such as morphine results in various emotional and physiological effects such as euphoria, nausea, lowered respiration and blood pressure, sedation, analgesia and constipation. In immunohistochemistry, OPRM1 has highest positivity in the cerebellum, basal ganglia, olfactory region, cerebral cortex and amygdala in the brain and is also highly expressed in seminiferous tubules in the testes. It has low levels of positivity in endocrine tissues. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human OPRM1 / Mu Opioid Receptor
Synonyms
OPRM1 | M-OR-1 | LMOR | MOR | Mu-type opioid receptor | HMOP | Opioid mu receptor | MOP | MOR-1 | MOR1 | Mu opioid receptor | Opioid receptor, mu 1 | KIAA0403 | MOR-1C | Mu opiate receptor | Mu opioid receptor hMOR-1a | Opioid mu-type receptor | OPRM
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd extracellular domain of human OPRM1 / Mu Opioid Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Opossum (100%); Mouse, Rat, Dog, Bat, Bovine, Hamster, Elephant, Horse, Pig (94%).
Epitope
Extracellular Domain
Specificity
Human OPRM1 / Mu Opioid Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (2.5 - 5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About OPRM1 / Mu Opioid Receptor
P35372 NM_000914 CAI20458.1

Validation

OPRM1 / Mu Opioid Receptor Antibody - Brain, Putamen
Brain, Putamen
Brain, Putamen

OPRM1 / Mu Opioid Receptor Antibody - Anti-OPRM1 / Mu Opioid Receptor antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OPRM1 / Mu Opioid Receptor antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-OPRM1 / Mu Opioid Receptor antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ OPRM1 / Mu Opioid Receptor Antibody (Extracellular Domain) for IHC LS-A233 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


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Requested From: United States
Date Requested: 12/22/2024