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| Catalog Number | Size | Price |
|---|---|---|
| LS-B5912-50 | 50 µg (0.5 mg/ml) | $485 |
1 of 2
2 of 2
PathPlus™ Polyclonal Goat anti‑Human NTN1 / Netrin 1 Antibody (aa591‑604, IHC, IF) LS‑B5912
PathPlus™ Polyclonal Goat anti‑Human NTN1 / Netrin 1 Antibody (aa591‑604, IHC, IF) LS‑B5912
Note: This antibody replaces LS-C112806
Antibody:
NTN1 / Netrin 1 Goat anti-Human Polyclonal (aa591-604) Antibody
Application:
IHC, IHC-P, IF, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Xenopus, Zebrafish
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
NTN1 / Netrin 1 Goat anti-Human Polyclonal (aa591-604) Antibody
Application:
IHC, IHC-P, IF, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Xenopus, Zebrafish
Format:
Unconjugated, Unmodified
Specifications
Description
NTN1 (Netrin 1) controls guidance of central nervous system commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. It is involved in the regulation of apoptosis in tumorigenesis.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human NTN1 / Netrin 1
Synonyms
NTN1 | Netrin 1 | Netrin 1, mouse, homolog of | Netrin-1 | NTN1L
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Xenopus, Zebrafish
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide with sequence KFQQREKKGKCKKA, from the C-Terminus of protein sequence according to NP_004813.2.
Epitope
aa591-604
Specificity
Human NTN1 / Netrin 1.
Applications
- IHC
- IHC - Paraffin (3.75 µg/ml)
- Immunofluorescence (10 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx. 70kDa band observed in Human Brain (Cerebellum), Mouse and Rat Brain lysates (calculated MW of 67.7kDa according to Human NP_004813.1 and 67.8kDa according to Rat NP_446183.1). Recommended concentration: 0.5-1.5 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NTN1 / Netrin 1
Validation
Anti-Netrin 1 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-Netrin 1 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
See More About...
LSBio Ratings
PathPlus™ NTN1 / Netrin 1 Antibody (aa591-604) for IHC, IF/Immunofluorescence LS-B5912 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human, Monkey, Mouse, Rat, Bovine, Pig, Sheep
Applications:
Western blot
Species:
Human, Monkey, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/21/2024
Date Requested: 12/21/2024
