NMUR1 is the G-protein coupled receptor for the neuromedin-U and neuromedin-S neuropeptides. Neuromedin U (NmU) belongs to the neuromedin family, comprising a series of neuropeptides involved in the gut–brain axis and including neuromedins B and C (bombesin-like), K (neurokinin B), L (neurokinin A or neurotensin), N, S, and U. These peptides have now been found to be expressed in several different tissues and have functions ranging from appetite regulation and energy balance control to muscle contraction and tumor progression. NMUR1 is expressed in diverse peripheral organs with relatively high levels in the small intestine and lung. References: DOI: 10.1373/clinchem.2014.231753; PLoS One. 2015; 10(8): e0136836.