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| Catalog Number | Size | Price |
|---|---|---|
| LS-B9544-50 | 50 µg (0.5 mg/ml) | $485 |
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PathPlus™ Polyclonal Goat anti‑Human IGF2 Antibody (aa81‑93, IHC) LS‑B9544
PathPlus™ Polyclonal Goat anti‑Human IGF2 Antibody (aa81‑93, IHC) LS‑B9544
Note: This antibody replaces LS-C154870
Antibody:
IGF2 Goat anti-Human Polyclonal (aa81-93) Antibody
Application:
IHC-P, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
IGF2 Goat anti-Human Polyclonal (aa81-93) Antibody
Application:
IHC-P, Peptide-ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF2 is a growth factor that serves as a potent mitogen and is involved in fetal development. It increases osteoblast mitogenic activity via phosphoactivation of MAPK1 and MAPK3. IGF2 is overexpressed in some rhabdomyosarcomas, and is of interest as a potential target of immune therapies.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; MC Cancer 19, 126 (2019) doi:10.1186/s12885-019-5339-4
Target
Human IGF2
Synonyms
IGF2 | C11orf43 | IGF-II | PP9974 | Somatomedin-A
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide with sequence ETYCATPAKSERD, from the internal region of the protein sequence according to NP_000603.1NP_001121070.1.
Epitope
aa81-93
Specificity
Human IGF2. This antibody is expected to recognize both reported isoforms (NP_000603.1; NP_001121070.1). Reported variants represent identical protein: NP_000603.1, NP_001007140.2
Applications
- IHC - Paraffin (5 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:64000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Preliminary experiments in Human Brain lysates gave no specific signal but low background (at antibody concentration up to 1 ug/ml).
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About IGF2
Validation
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-IGF-II / IGF2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-IGF-II / IGF2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ IGF2 Antibody (aa81-93) for IHC LS-B9544 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
