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| Catalog Number | Size | Price |
|---|---|---|
| LS-A443-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human GPR78 Antibody (Cytoplasmic Domain, IHC) LS‑A443
PathPlus™ Polyclonal Rabbit anti‑Human GPR78 Antibody (Cytoplasmic Domain, IHC) LS‑A443
Antibody:
GPR78 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
GPR78 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
G protein-coupled receptor 78 (GPR78) is an orphan GPCR that shares sequence homology with GPR26, and is widely expressed in selective regions of the brain. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene.
References: Molecular Psychiatry (2006) 11, 384–394; BBA Volume 1770, Issue 6, June 2007, Pages 890-901
Target
Human GPR78
Synonyms
GPR78 | G protein-coupled receptor 78 | G-protein coupled receptor 78
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human GPR78. Percent identity with other species by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Orangutan, Gibbon (94%); Monkey (88%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR78. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (14 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GPR78
Validation
Brain, Alzheimer's disease, neurofibrillary tangles
Brain, Alzheimer's disease, neurofibrillary tangles
Brain, Alzheimer's disease, senile plaque
Brain, Alzheimer's disease, senile plaque
Brain, Alzheimer's disease, neurofibrillary tangles
Brain, Alzheimer's disease, neurofibrillary tangles
Anti-GPR78 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR78 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR78 antibody IHC of human placenta, villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR78 antibody IHC of human placenta, villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ GPR78 Antibody (Cytoplasmic Domain) for IHC LS-A443 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/24/2024
Date Requested: 12/24/2024
