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| Catalog Number | Size | Price |
|---|---|---|
| LS-A88-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human GPR17 Antibody (Cytoplasmic Domain, IHC) LS‑A88
PathPlus™ Polyclonal Rabbit anti‑Human GPR17 Antibody (Cytoplasmic Domain, IHC) LS‑A88
Antibody:
GPR17 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
GPR17 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
G protein-coupled receptor 17 (GPR17) is a dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). It signals through G(i) and inhibition of adenylyl cyclase. GPR17 mediates brain damage by nucleotides and CysLTs following ischemia. In immunohistochemistry, GPR17 has membranous positivity on astrocytes throughout the brain and nervous system and in populations of immune cells.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GPR17
Synonyms
GPR17 | G protein-coupled receptor 17 | G-protein coupled receptor 17 | p2Y-like receptor | Y12546 | Z94155 | R12 | UDP/CysLT receptor
Host
Rabbit
Reactivity
Human, Monkey, Bovine, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from 1st cytoplasmic domain of human GPR17. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Horse, Rabbit, Pig (100%); Mouse, Rat, Opossum (93%); Hamster, Chicken, Platypus (87%); Turkey, Lizard (80%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR17. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (3 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Failed Applications
- ICC
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GPR17
Validation
Anti-GPR17 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR17 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR17 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR17 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR17 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR17 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ GPR17 Antibody (Cytoplasmic Domain) for IHC LS-A88 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC
Species:
Human, Chicken
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
