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| Catalog Number | Size | Price |
|---|---|---|
| LS-A6576-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human GHSR / Ghrelin Receptor Antibody (N‑Terminus, IHC) LS‑A6576
PathPlus™ Polyclonal Rabbit anti‑Human GHSR / Ghrelin Receptor Antibody (N‑Terminus, IHC) LS‑A6576
Antibody:
GHSR / Ghrelin Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
GHSR / Ghrelin Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Growth hormone secretagogue receptor (GHSR) / Ghrelin Receptor plays a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in GHSR are associated with autosomal idiopathic short stature.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GHSR / Ghrelin Receptor
Synonyms
GHSR | GHS receptor | GH secretagogue receptor | GHRP | GHS-R | GH-releasing peptide receptor | Ghrelin receptor | Ghrp receptor
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 13 amino acid peptide from N-Terminus extracellular domain of human Ghrelin Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (92%); Mouse, Rat (85%).
Epitope
N-Terminus
Specificity
Human Ghrelin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BAIAP3 (77%).
Applications
- IHC
- IHC - Paraffin (5 - 7.5 µg/ml)
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GHSR / Ghrelin Receptor
Validation
Brain, pituitary
Brain, pituitary
Adrenal
Adrenal
Anti-Ghrelin Receptor antibody IHC of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Ghrelin Receptor antibody IHC of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GHSR / Ghrelin Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GHSR / Ghrelin Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ GHSR / Ghrelin Receptor Antibody (N-Terminus) for IHC, ELISA LS-A6576 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat
Applications:
Western blot, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin
Reactivity:
Human
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
