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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1878-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human FPR2 / FPRL1 Antibody (Extracellular Domain, IHC) LS‑A1878
PathPlus™ Polyclonal Rabbit anti‑Human FPR2 / FPRL1 Antibody (Extracellular Domain, IHC) LS‑A1878
Antibody:
FPR2 / FPRL1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
FPR2 / FPRL1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Formyl peptide receptor 2 (FPR2) functions as a component of the inflammatory response. FPR2 stimulation results in neutrophil activation and desensitization of chemokine receptors in monocytes (Le et al., 2000). FPR2 is up-regulated by interleukin-1 in normal human synovial fibroblasts. The immunodeficiency virus type 1 (HIV-1) envelope protein gp41 can activate the innate host immune cells through FPRL1 and induces directional migration and calcium mobilization in human monocytes and neutrophils. Recently, FPR2 has been implicated in Alzheimer's Disease.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human FPR2 / FPRL1
Synonyms
FPR2 | ALXR | FMLP-R-I | FMLP-related receptor I | Fpr-rs1 | FPRL1 | FPR-like 1 | Fprl-1 | HM63 | FMLP-R-II | FMLPX | Formyl peptide receptor-like 1 | FPR2A | FPRH1 | FPRH2 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin receptor | N-formyl peptide receptor 2 | Formyl peptide receptor 2
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from 2nd extracellular domain of human FPR2 / FPRL1. Percent identity with other species by BLAST analysis: Human (100%); Chimpanzee, Gorilla, Monkey (95%); Orangutan (90%); Dog (85%).
Epitope
Extracellular Domain
Specificity
Human FPR2 / FPRL1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FPR3 (50%).
Applications
- IHC
- IHC - Paraffin (5 - 7.5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About FPR2 / FPRL1
Validation
Lung, Adenocarcinoma
Lung, Adenocarcinoma
Adipocytes
Adipocytes
Anti-FPR2 / FPRL1 antibody IHC of human bone marrow. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FPR2 / FPRL1 antibody IHC of human bone marrow. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ FPR2 / FPRL1 Antibody (Extracellular Domain) for IHC LS-A1878 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
Immunofluorescence, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
