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Catalog Number Size Price
LS-B13715-50 50 µl (1 mg/ml) $460 
FLG / Filaggrin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
FLG / Filaggrin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
FLG / Filaggrin Antibody - Western blot analysis of Filaggrin expression in HeLa (A); NS-1 (B); PC12 (C) whole cell lysates.
FLG / Filaggrin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
FLG / Filaggrin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
FLG / Filaggrin Antibody - Western blot analysis of Filaggrin expression in HeLa (A); NS-1 (B); PC12 (C) whole cell lysates.
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PathPlus™ Polyclonal Rabbit anti‑Human FLG / Filaggrin Antibody (N‑Terminus, IHC, WB) LS‑B13715

PathPlus™ Polyclonal Rabbit anti‑Human FLG / Filaggrin Antibody (N‑Terminus, IHC, WB) LS‑B13715

Note: This antibody replaces LS-C358751
Antibody:
FLG / Filaggrin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B13715-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
FLG / Filaggrin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
FLG (Filaggrin) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 amino acids each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris. In immunohistochemistry, FLG has cytoplasmic positivity in superficial squamous epithelium in oral mucosa, the esophagus, female reproductive tissues, skin and tonsils. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804;
Target
Human FLG / Filaggrin
Synonyms
FLG | ATOD2 | Epidermal filaggrin | Filaggrin
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-Terminus of human Filaggrin.
Epitope
N-Terminus
Specificity
Recognizes endogenous levels of Filaggrin protein.
Applications
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About FLG / Filaggrin
P20930 NM_002016 NP_002007.1

Validation

FLG / Filaggrin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

FLG / Filaggrin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ FLG / Filaggrin Antibody (N-Terminus) for IHC, WB/Western LS-B13715 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/22/2024