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Catalog Number	Size	Price
LS-A6600-50	50 µg (1 mg/ml)	$440

FFAR2 / GPR43 Antibody - Brain, Glioblastoma

FFAR2 / GPR43 Antibody - Brain, Hypothalamus

FFAR2 / GPR43 Antibody - Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FFAR2 / GPR43 Antibody - Anti-FFAR2 / GPR43 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FFAR2 / GPR43 Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)

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PathPlus™ Polyclonal Rabbit anti‑Human FFAR2 / GPR43 Antibody (Extracellular Domain, IHC) LS‑A6600

Name: PathPlus™ FFAR2 / GPR43 Polyclonal Antibody Rabbit anti-Human | LSBio
Brand: Lifespan BioSciences
SKU: LS-A6600-50
Price: 440.0000 USD
Availability: InStock
Rating: 5 (1 reviews)

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Antibody:

FFAR2 / GPR43 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody

Application:

IHC, IHC-P

Reactivity:

Human

Format:

Unconjugated, Unmodified

$440

LS-A6600-50

Ready To Ship

Toll Free North America

(800) 227-6666

For Research Use Only

Specifications Validation Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

FFAR2 / GPR43 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody

Application:

IHC, IHC-P

Reactivity:

Human

Format:

Unconjugated, Unmodified

Specifications

Description

Free fatty acid receptor 2 (FFAR2) is a G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. FFAR2 regulates the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake and the whole-body's energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. FFAR2 plays a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804

Target

Human FFAR2 / GPR43

Synonyms

See All FFAR2 / GPR43 Antibodies

Host

Rabbit

Reactivity

Human (tested or 100% immunogen sequence identity)

Predicted

Monkey (at least 90% immunogen sequence identity)

Clonality

Polyclonal

Conjugations

Unconjugated

Purification

Immunoaffinity purified

Modifications

Unmodified

Immunogen

Synthetic 17 amino acid peptide from 2nd extracellular domain of human GPR43. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Mouse, Rat, Dog, Panda, Rabbit, Pig (88%); Horse, Opossum (82%).

Epitope

Extracellular Domain

Specificity

Human GPR43. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FFAR3 (47%).

Applications

IHC
IHC - Paraffin (5 - 10 µg/ml)

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Presentation

PBS, 0.1% Sodium Azide

Storage

Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About FFAR2 / GPR43

Uniprot: O15552 NCBI: NM_005306 NP_005297.1

Validation

Brain, Glioblastoma

Brain, medulla

Brain, Hypothalamus

Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-FFAR2 / GPR43 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-FFAR2 / GPR43 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.