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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2890-100 | 100 µg | $460 |
PathPlus™ Monoclonal Mouse anti‑Human ENO2 / NSE Antibody (clone NSE‑P1, IHC, WB) LS‑B2890
PathPlus™ Monoclonal Mouse anti‑Human ENO2 / NSE Antibody (clone NSE‑P1, IHC, WB) LS‑B2890
Note: This antibody replaces LS-C62804
Antibody:
ENO2 / NSE Mouse anti-Human Monoclonal (NSE-P1) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ENO2 / NSE Mouse anti-Human Monoclonal (NSE-P1) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
NSE (neuron-specific enolase, ENO2) is a metalloenzyme involved in neural tissue development. In immunohistochemistry, NSE is a positive marker for neurons and neuroendocrine cells, and it is also positive in islets of Langerhans of the pancreas. In cancers, it is positive in neuroendocrine tumors such as carcinoid and schwannoma. NSE is a useful marker of disease status and prognosis in small-cell lung cancer, prostate cancer and acute lymphoblastic leukemia where elevated levels may indicate progression.
References: Br J Cancer. 1994 Oct; 70(4): 759–761, PMID: 7917935; Int J Biol Markers. 2018 Jan;33(1):10-21, PMID: 28885659; Cell Physiol Biochem. 2018;46(4):1525-1535, PMID: 29689546; Int J Clin Exp Med. 2015; 8(6): 9498–9504, PMID: 26309614
Target
Human ENO2 / NSE
Synonyms
ENO2 | Enolase 2 | Enolase 2 (gamma, neuronal) | Neurone-specific enolase | Gamma-enolase | Neural enolase | Neuron specific gamma enolase | Neuron-specific enolase | NSE
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
NSE-P1
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Enolase of human origin
Specificity
Anti neuron-specific enolase 1 (NSE-P1, ENO1, Enolase 1, 2-Phospho-D-Glycerate Hydrolase, alpha enolase, ay) is an 80 kD protein and one of the five isozymes of enolase, a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and p.
Applications
- IHC
- IHC - Paraffin (20 µg/ml)
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2890 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2890 was determined to be 20 ug/ml.
Presentation
PBS, 0.02% Sodium Azide
Storage
Short term 4°C (no longer than 1 week); Long term -20°C; Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ENO2 / NSE
Validation
Anti-NSE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Anti-NSE antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
See More About...
LSBio Ratings
PathPlus™ ENO2 / NSE Antibody (clone NSE-P1) for IHC, WB/Western, ELISA LS-B2890 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Fluorescence- and magnetic-activated cell sorting strategies to isolate and enrich human spermatogonial stem cells. Valli H, Sukhwani M, Dovey SL, Peters KA, Donohue J, Castro CA, Chu T, Marshall GR, Orwig KE. Fertility and sterility. 2014 Aug;102:566-580.e7.
Customer Reviews (0)
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
