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| Catalog Number | Size | Price |
|---|---|---|
| LS-B12925-0.1 | 0.1 mg (1 mg/ml) | $460 |
PathPlus™ Monoclonal Mouse anti‑Human CGB / hCG Beta Antibody (clone INN‑hCG‑22, Beta 2, IHC, IF, WB) LS‑B12925
PathPlus™ Monoclonal Mouse anti‑Human CGB / hCG Beta Antibody (clone INN‑hCG‑22, Beta 2, IHC, IF, WB) LS‑B12925
Note: This antibody replaces LS-C45071
Antibody:
CGB / hCG Beta Mouse anti-Human Monoclonal (Beta 2) (INN-hCG-22) Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CGB / hCG Beta Mouse anti-Human Monoclonal (Beta 2) (INN-hCG-22) Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Beta Human Chorionic Gonadotrophin (beta hCG, CGB) is a human glycoprotein hormone expressed by placental trophoblasts that stimulate ovaries to synthesize steroids needed to maintain pregnancy. HCG is a useful marker for detecting pregnancy, as well as identifying choriocarcinomas or tumors of syncytiotrophoblasts. Serum levels of HCG are also used to stage gestational trophoblastic tumors or germ cell tumors. HCG is positive in placental trophoblasts, germ cell tumors, choriocarcinomas, granulosa cell tumors, hydatidiform mole, invasive colorectal cancer, serous effusions with reactive mesothelium, and testicular seminomas with syncytiotrophoblasts.
References: Mod Pathol 2004;17:701, PMID: 15001996; Cell Physiol Biochem. 2018;45(1):237-249, PMID: 29357321
Target
Human CGB / hCG Beta
Synonyms
CGB | CGB3 | CG-beta | HCGB | hCG Beta
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
INN-hCG-22
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
HCG
Epitope
Beta 2
Specificity
Shows strong reaction in RIA with hCG and b-hCG with some reactivity on hLH (12%) and b-hLH (34%). No reaction with hFSH, hTSH, a-hCG and a-hLH. Affinity constant = 1.6 x 109m (Ka).
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Immunofluorescence
- Western blot
- ELISA (1:100 - 1:500)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
For Western blot use non-reducing conditions.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CGB / hCG Beta
Validation
Human Placenta, trophoblasts: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta, trophoblasts: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ CGB / hCG Beta Antibody (Beta 2, clone INN-hCG-22) for IHC, IF/Immunofluorescence, WB/Western, ELISA LS-B12925 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
