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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4299-100 | 100 µg (0.34 mg/ml) | $485 |
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PathPlus™ Monoclonal Mouse anti‑Human CDX2 Antibody (clone 1C7, IHC, WB) LS‑B4299
PathPlus™ Monoclonal Mouse anti‑Human CDX2 Antibody (clone 1C7, IHC, WB) LS‑B4299
Note: This antibody replaces LS-C104916
Antibody:
CDX2 Mouse anti-Human Monoclonal (1C7) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CDX2 Mouse anti-Human Monoclonal (1C7) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
CDX2 codes for a homeobox protein involved in intestinal cell differentiation and tumor suppression in the colon. Loss of expression of this protein is correlated with colorectal tumorigenesis and poor survival. The protein is expressed in the nuclei of colonic epithelial cells and in colorectal cancers. Positive staining can also be found in a variety of other tumors such as teratomas, small intestinal carcinomas, bile duct cancers, Barrett’s intestinal metaplasia, and some cases of uothelial cancer. Staining is expected to be nuclear.
References: Platet, 2017; Dalerba, 2016; Human Pathol 2011, 42:1653; Am J Clin Path 2008, 130:265
Target
Human CDX2
Synonyms
CDX2 | Caudal-type homeobox protein 2 | CDX3 | Homeobox protein CDX-2 | Caudal type homeobox 2 | CDX-3
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Monoclonal
Clone
1C7
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
CDX2 (AAH14461, 1 aa ~ 314 aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot (Tissue lysate) - positive control human parotid gland. Western Blot (Cell lysate) - positive control COLO 320 HSR. Sandwich ELISA (Recombinant protein).
Presentation
PBS, pH 7.4
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CDX2
Validation
Anti-CDX2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-CDX2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
PathPlus™ CDX2 Antibody (clone 1C7) for IHC, WB/Western, ELISA LS-B4299 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Temporal and spatial expression of caudal-type homeobox proteins in the midgut of human embryos. Tang XB, Zhang J, Wang WL, Yuan ZW, Bai YZ. International journal of clinical and experimental medicine. 2016 8:19895-904. (ICC, WB; Human)
Spatiotemporal distribution of caudal-type homeobox proteins during development of the hindgut and anorectum in human embryos. Tang XB, Zhang T, Wang WL, Yuan ZW, Bai YZ. PeerJ. 2016 4:e1771. (ICC, WB; Human)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Bovine, Horse, Opossum
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
