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ADRB2

adrenoceptor beta 2, surface

ADRB2 is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Gene Name: adrenoceptor beta 2, surface
Family/Subfamily: GPCR , Adrenergic
Synonyms: ADRB2, ADRB2R, Adrenoceptor beta 2, surface, ADRBR, B2AR, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, BETA2AR, BAR, Adrenergic beta-2 receptor, Catecholamine receptor
Target Sequences: NM_000024 NP_000015.1 P07550

Publications (4)

1
Matrix metalloproteinases cleave the beta2-adrenergic receptor in spontaneously hypertensive rats. Rodrigues SF, Tran ED, Fortes ZB, Schmid-Schnbein GW. American journal of physiology. Heart and circulatory physiology. 2010 299:H25-35. [PubMed:20382857] [PMC:PMC2904131]
2
ß-Adrenergic receptor subtype expression in myocyte and non-myocyte cells in human female bladder. Limberg BJ, Andersson KE, Aura Kullmann F, Burmer G, de Groat WC, Rosenbaum JS. Cell and tissue research. 2011 317:107-16. (ICC, IHC-P; Human) [Full Text Article] [PubMed:20953633] [PMC:PMC3113530] Related Antibodies: LS-A2662.
3
Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity. Hagberg CE, Li Q, Kutschke M, Bhowmick D, Kiss E, Shabalina IG, Harms MJ, Shilkova O, Kozina V, Nedergaard J, Boucher J, Thorell A, Spalding KL. Cell reports. 2018 September;24:2746-2756. [Full Text Article] [PubMed:30184507] [PMC:PMC6137819] Related Antibodies: LS-C274967.
4
Clenbuterol and formoterol decrease force production in isolated intact mouse skeletal muscle fiber bundles through a beta2-adrenoceptor-independent mechanism. McCormick C, Alexandre L, Thompson J, Mutungi G. Journal of applied physiology (Bethesda, Md. : 1985). 2010 Dec;109:1716-27. [Full Text Article] [PubMed:20864554] Related Antibodies: LS-C54456.
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☰ Filters
Antibodies (87)
ELISA Kits (13)
Proteins (4)
Cell-Based (2)
Cell-Based Phosphorylation (2)
Custom (4)
Over-Expression Lysate (2)
Primary (87)
Recombinant (2)
Sandwich (5)
ADRB2 (104)
Human (87)
Mouse (37)
Rat (25)
Bovine (4)
Chimpanzee (4)
Dog (4)
Guinea pig (3)
Hamster (1)
Horse (1)
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Sheep (3)
IHC (35)
IHC-P (11)
WB (68)
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DB (7)
ELISA (43)
FLISA (1)
Func (2)
ICC (3)
IF (16)
IP (2)
Peptide-ELISA (10)
rabbit (80)
mouse (5)
goat (1)
chicken (1)
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monoclonal mc (4)
polyclonal pc (83)
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Ser261 (7)
Ser364 (7)
Thr384 (7)
pSer261 (7)
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pSer346 (6)
aa330-418 (4)
290-370 aa (2)
300-380 aa (2)
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Cys378 (1)
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Leu342 (1)
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Transmembrane Domain (1)
aa1-413 (1)
aa201-250 (1)
aa221-256 (1)
aa3-21 (1)
aa321-370 (1)
aa329-378 (1)
aa335-408 (1)
aa336-385 (1)
aa390-402 (1)
p346 (1)
pSer355+Ser356 (1)
pSer355/356 (1)
No (101)
Yes (3)
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Human (3)
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Purified (2)
ADRB2 Antibody - Anti-ADRB2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2.8-4.6 ug/ml.
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ADRB2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
ADRB2 Antibody - Antibody (0.2 ug/ml) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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ADRB2 Goat anti-Human Polyclonal (aa390-402) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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ADRB2 Mouse anti-Human Monoclonal (13A16) Antibody
Guinea pig, Rat, Human
ELISA, Flo, Func
Unconjugated
100 µg/$866
ADRB2 Antibody - Western blot analysis of Beta-2 Adrenergic Receptor expression in HepG2 (A); mouse kidney (B); rat kidney (C) whole cell lysates.
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ADRB2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Human
WB
Unconjugated
100 µl/$299
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ADRB2 Chicken anti-Human Polyclonal (aa335-408) Antibody
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Horse, Human, Monkey
WB
Unconjugated
50 µg/$807
ADRB2 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
ADRB2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$783
ADRB2 Antibody - Western blot of AR-beta2 antibody
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ADRB2 Rabbit anti-Human Polyclonal (300-380 aa) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADRB2 Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ADRB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADRB2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Adrenergic Receptor beta2 Antibody. The picture on the right is blocked with the synthesized peptide.
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ADRB2 Rabbit anti-Human Polyclonal (aa321-370) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ADRB2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using Adrenergic Receptor beta2 (Phospho-Ser346) Antibody. The picture on the right is blocked with the phospho peptide.
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ADRB2 Rabbit anti-Human Polyclonal (pSer346) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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ADRB2 Rabbit anti-Human Polyclonal (Ser364) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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ADRB2 Rabbit anti-Human Polyclonal (Ser364) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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ADRB2 Rabbit anti-Human Polyclonal (Ser364) (APC) Antibody
Human
ELISA, FLISA, WB
APC Conjugated
200 µl/$952
ADRB2 Antibody - Anti-ADRB2 antibody IHC of human heart, cardiac myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ADRB2 Rabbit anti-Human Polyclonal (Transmembrane Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ADRB2 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
ADRB2 Antibody - Anti-ADRB2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADRB2 Rabbit anti-Human Polyclonal (aa336-385) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ADRB2 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using ADRB2 Polyclonal Antibody at dilution of 1:20.
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ADRB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADRB2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using Adrenergic Receptor B2 (Phospho-Ser355+Ser356) Antibody. The picture on the right is blocked with the phospho peptide.
Select
ADRB2 Rabbit anti-Human Polyclonal (pSer355/356) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
ADRB2 Rabbit anti-Human Polyclonal (300-380 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
ADRB2 Rabbit anti-Human Polyclonal (aa3-21) Antibody
Human
IHC, IP, WB
Unconjugated
50 µl/$393
ADRB2 Antibody - Immunofluorescence analysis of NIH/3T3 cells, using ADRB2 Antibody. The picture on the right is blocked with the synthesized peptide.
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ADRB2 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
ADRB2 Mouse anti-Human Monoclonal (6H8) Antibody
Guinea pig, Rat, Human
Flo, Func
Unconjugated
100 µg/$589
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ADRB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IP, WB
Unconjugated
100 µl/$749
ADRB2 Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
ADRB2 Rabbit anti-Human Polyclonal (pSer346) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 104 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).