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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1138-50 | 50 µg (1 mg/ml) | $440 |
1 of 3
2 of 3
3 of 3
PathPlus™ Polyclonal Rabbit anti‑Human ADGRL3 / LPHN3 Antibody (C‑Terminus, IHC) LS‑A1138
PathPlus™ Polyclonal Rabbit anti‑Human ADGRL3 / LPHN3 Antibody (C‑Terminus, IHC) LS‑A1138
Antibody:
ADGRL3 / LPHN3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Horse, Rabbit, Chicken
Format:
Unconjugated, Unmodified
Overview
Antibody:
ADGRL3 / LPHN3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Horse, Rabbit, Chicken
Format:
Unconjugated, Unmodified
Specifications
Description
Latrophilin 3 (ADGRL3) is a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human ADGRL3 / LPHN3
Synonyms
ADGRL3 | CIRL3 | CIRL-3 | Lectomedin 3 | Lectomedin-3 | Lph3 | KIAA0768 | Latrophilin 3 | Latrophilin homolog 3 (cow) | LPHN3 | Cl3 latrotoxin receptor | Latrophilin-3 | LEC3
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Horse, Rabbit, Chicken
(tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from C-Terminus of human LPHN3. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Bat, Elephant, Panda, Horse, Rabbit, Opossum, Turkey, Chicken, Lizard (100%); Bovine, Platypus (95%); Gibbon (89%).
Epitope
C-Terminus
Specificity
Human LPHN3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (2 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADGRL3 / LPHN3
Validation
Brain, hippocampus CA3
Brain, hippocampus CA3
Brain, Medulla
Brain, Medulla
Anti-LPHN3 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-LPHN3 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ ADGRL3 / LPHN3 Antibody (C-Terminus) for IHC LS-A1138 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Hamster, Horse, Chicken
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/25/2024
Date Requested: 12/25/2024
