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| Catalog Number | Size | Price |
|---|---|---|
| LS-A2021-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human ADGRF1 / GPR110 Antibody (N‑Terminus, IHC) LS‑A2021
PathPlus™ Polyclonal Rabbit anti‑Human ADGRF1 / GPR110 Antibody (N‑Terminus, IHC) LS‑A2021
Antibody:
ADGRF1 / GPR110 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
ADGRF1 / GPR110 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
G Protein-Coupled Receptor GPR110 is a GPCR targeted by N-docosahexaenoylethanolamine (DHA), a fatty acid essential for brain development. GPR110 is a receptor involved in mediating the bioactivity of synaptamides in a cAMP dependent manner, and is involved in promoting neurogenesis and synaptogenesis. It has also been implicated as an oncogene in lung and prostate cancer.
References: Nature Communications volume 7, Article number: 13123 (2016; BMC Cancer volume 10, Article number: 40 (2010
Target
Human ADGRF1 / GPR110
Synonyms
ADGRF1 | G protein-coupled receptor 110 | G-protein coupled receptor 110 | GPR110 | HGPCR36 | KPG_012 | PGR19
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from N-Terminus extracellular domain of human GPR110. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Marmoset (88%).
Epitope
N-Terminus
Specificity
Human GPR110. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (5 - 10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADGRF1 / GPR110
Validation
Brain, Cortex, Neurons and glia
Brain, Cortex, Neurons and glia
Brain, Medulla
Brain, Medulla
Anti-GPR110 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR110 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR110 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR110 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR110 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR110 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ ADGRF1 / GPR110 Antibody (N-Terminus) for IHC LS-A2021 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer. Lum AM, Wang BB, Beck-Engeser GB, Li L, Channa N, Wabl M. BMC cancer. 2010 10:40. (IHC-P; Human)
Synaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding. Bill X Huang, Xin Hu, Heung-Sun Kwon, Cheng Fu, Ji-Won Lee, Noel Southall, Juan Marugan, Hee-Yong Kim. Communications biology. 2020 Mar;3:109.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
Western blot, Immunoprecipitation
Species:
Human, Mouse
Applications:
IHC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
