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| Catalog Number | Size | Price |
|---|---|---|
| LS-B11114-100 | 100 µl | $460 |
1 of 2
2 of 2
PathPlus™ Polyclonal Rabbit anti‑Human ACTG2 Antibody (aa343‑371, IHC, WB) LS‑B11114
PathPlus™ Polyclonal Rabbit anti‑Human ACTG2 Antibody (aa343‑371, IHC, WB) LS‑B11114
Note: This antibody replaces LS-C155995
Antibody:
ACTG2 Rabbit anti-Human Polyclonal (aa343-371) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ACTG2 Rabbit anti-Human Polyclonal (aa343-371) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Smooth muscle gamma actin (ACTG2) is a protein that is a component of the cytoskeleton in smooth muscle and is involved in cell motility. Mutations of the ACTG2 gene result in visceral myopathy, a rare form of myopathic pseudo-obstruction. ACTG2 is localized to the cytoplasm of myoepithelial cells, predominantly in enteric tissues. Aberrant expression has been reported in several types of cancer such as colorectal, breast, laryngeal, and small intestinal neuroendocrine tumors, which may affect chemotherapy sensitivity. Staining is used to identify smooth muscle cells in normal tissue and in disease.
References:
Mol Cell Biol. 1991;11(6):3296-3306. PMID: 1710027; PLoS Genet. 2014;10(3):e1004258. doi: 10.1371/journal.pgen.1004258; BMC Endocr Disord. 2016;16:19. doi: 10.1186/s12902-016-0100-3; Cancer Biother Radiopharm. 2013;28(7): 552-558. doi: 10.1089/cbr.2012.1431; Acta Oncol. 2007;46(5):651-658. doi: 10.1080/02841860601156157; Int J Clin Exp Pathol. 2013;6(7):1351-1361. PMID: 23826416
Target
Human ACTG2
Synonyms
ACTG2 | ACTA3 | Actin-like protein | ACTSG | ACTE | Actin, alpha cardiac | ACTL3 | Alpha-actin 3 | Alpha-actin-3 | Smooth muscle gamma-actin | Gamma-2-actin | Smooth muscle gamma actin
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Chicken, Cow (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Epitope
aa343-371
Specificity
This ACTG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human ACTG2.
Applications
- IHC
- IHC - Paraffin (1:100)
- Western blot (1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ACTG2
Validation
Anti-ACTG2 antibody IHC staining of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-ACTG2 antibody IHC staining of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
See More About...
LSBio Ratings
PathPlus™ ACTG2 Antibody (aa343-371) for IHC, WB/Western LS-B11114 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat, Bovine, Rabbit, Chicken
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/22/2024
Date Requested: 12/22/2024
