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Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.
Gene Name: | VANGL planar cell polarity protein 2 |
Synonyms: | VANGL2, KIAA1215, Loop-tail-associated protein, LTAP, STBM, Loop-tail protein 1 homolog, LPP1, STB1, STBM1, Strabismus 1, Vang-like protein 2, Van Gogh-like protein 2 |
Target Sequences: | AB033041 BAA86529.1 Q9ULK5 |
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