Human UPK3A / UPK3 / Uroplakin III

Rabbit

Human, Orangutan (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Protein A purified

Azide-free, BSA-free. Also available Unmodified.

A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A. Percent identity by BLAST analysis: Human, Orangutan (100%); Gorilla (95%); Monkey, Marmoset, Ferret, Pig (90%); Mouse, Rabbit, Dog (85%); Horse (80%).

aa260-279

Human UPK3A / UPK3 / Uroplakin III

• Immunofluorescence (1 - 2 µg/ml)
• Western blot (0.5 - 1 µg/ml)
• Immunoprecipitation
• Flow Cytometry (0.5 - 1 µg/10E6 cells)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.

1X PBS

Store at 2-8°C (with azide) or aliquot and store at -20°C (without azide).

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: O75631 NCBI: NM_006953 NP_008884.1