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| Catalog Number | Size | Price |
|---|---|---|
| LS-B1654-50 | 50 µl (0.35 mg/ml) | $460 |
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IHC‑plus™ Polyclonal Rabbit anti‑Human Tuberin / TSC2 Antibody (phospho‑Ser664, IHC, IF) LS‑B1654
IHC‑plus™ Polyclonal Rabbit anti‑Human Tuberin / TSC2 Antibody (phospho‑Ser664, IHC, IF) LS‑B1654
Note: This antibody replaces LS-C41185
Antibody:
Tuberin / TSC2 Rabbit anti-Human Polyclonal (pSer664) Antibody
Application:
IHC, IHC-P, ICC, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
Tuberin / TSC2 Rabbit anti-Human Polyclonal (pSer664) Antibody
Application:
IHC, IHC-P, ICC, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
TSC2 antibody LS-B1654 is an unconjugated rabbit polyclonal antibody to human TSC2 (Tuberin) (pSer664). Validated for ICC, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Target
Human Tuberin / TSC2
Synonyms
TSC2 | LAM | Tuberous sclerosis 2 protein | TSC4 | Tuberin | Tuberous sclerosis 2
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human TSC2.
Epitope
pSer664
Specificity
Modified peptide
Applications
- IHC
- IHC - Paraffin (1:50)
- ICC
- Immunofluorescence
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B1654 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1654 was determined to be 1:50.
Presentation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About Tuberin / TSC2
Validation
Anti-TSC2 / Tuberin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-TSC2 / Tuberin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
See More About...
LSBio Ratings
IHC-plus™ Tuberin / TSC2 Antibody (phospho-Ser664) for IHC, ICC, IF/Immunofluorescence LS-B1654 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation. Bartolom A, Guilln C, Benito M. Endocrinology. 2010 151:3084-94.
Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling. Miyazaki M, McCarthy JJ, Fedele MJ, Esser KA. The Journal of physiology. 2011 589:1831-46.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
Immunofluorescence, Dot Blot
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Monkey, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Reactivity:
Human, Mouse, Rat
Range:
Positive/Negative
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/22/2024
Date Requested: 12/22/2024
