Target
Human TPM3
Synonyms
TPM3 | CFTD | Cytoskeletal tropomyosin TM30 | Gamma-tropomyosin | NEM1 | Hscp30 | TM30nm | Tropomyosin alpha-3 chain | TM-5 | TM5 | TPMsk3 | Tropomyosin 3 | Tropomyosin-5 | TM3 | TM30 | TRK | Tropomyosin-3 | HTM5 | OK/SW-cl.5 | Tropomyosin gamma
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
FITC,
Biotin.
Immunogen
Recombinant Human Tropomyosin alpha-3 chain protein (18-224AA)
Specificity
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.