Human TP63 / p63

Rabbit

Human, Monkey, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Affinity purified

Unmodified

Synthetic peptide C-NFDMDARRNKQQRIKEEGE corresponding to amino acids 662-680 within the C-Terminus of p63. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Ferret, Elephant, Panda, Bovine, Dog, Cat, Horse, Rabbit, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus (100%); Marmoset, Mouse, Rat, Hamster (95%); Xenopus (89%); Pufferfish (84%).

aa662-680

Specifically recognizes an epitope within the C-terminal (CT) region of tumor protein p63, otherwise known as tumor protein p73-like (p73L), a widely expressed nuclear protein and homologue of tumor suppressor p53, which acts as a sequence-specific DNA binding transcriptional activator/repressor. p63, vital for the development of the prostate and selectively expressed by normal prostate basal cells, has been shown to be a promising complementary basal cell specific marker to High Molecular Weight-Cytokeratin (HMW-CK), for the differential diagnosis of benign prostatic lesions and prostatic carcinoma. The antibody is reported as suitable for use in immunocytochemistry.

• Western blot (1:1000)
• ELISA (1:100000)

PBS, 0.09% Sodium Azide, 0.1% BSA

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q9H3D4 NCBI: NM_003722 NP_003713.3