Human TACR3 / NK3R

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Affinity purified

Unmodified

An 18 amino acid peptide near the centre of human TACR3.

Recognizes human TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kD multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. Studies with mice indicate that TACR3 is involved in learning and memory. AHP1492 does not recognize NK1R or NK2R.

• IHC
• IHC - Paraffin (5 µg/ml)
• Western blot (0.5 - 1 µg/ml)

Western Blot: LS-C56946 detects a band of approximately 46kD in RAW264.7 cell lysates. Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

PBS, 0.02% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P29371 NCBI: NM_001059 NP_001050.1