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SRRT / ARS2

serrate RNA effector molecule homolog (Arabidopsis)

Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription.

Gene Name: serrate RNA effector molecule homolog (Arabidopsis)
Synonyms: SRRT, Arsenate resistance protein 2, ARS2, Serrate, Arsenite resistance protein, Arsenite-resistance protein 2, ASR2
Target Sequences: NM_015908 NP_056992.4 Q9BXP5

☰ Filters
Antibodies (15)
Proteins (5)
Over-Expression Lysate (2)
Primary (15)
Recombinant (3)
SRRT / ARS2 (20)
Human (15)
Mouse (6)
Rat (2)
Zebrafish (1)
IHC (3)
IHC-P (2)
WB (14)
ELISA (8)
IP (2)
Peptide-ELISA (3)
rabbit (13)
goat (1)
rabbit-new zealand white (1)
Product Group
IHCPlus (2)
IgG (9)
polyclonal pc (15)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (10)
aa54-81 (7)
C-Terminus (1)
aa1-50 (1)
aa627-876 (1)
aa733-766 (1)
aa826-876 (1)
aa878-910 (1)
No (20)
DDK,C-terminus (1)
GST (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Sf9 Cells (1)
Wheat Germ Extract (1)
Purified (1)
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$379
SRRT / ARS2 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
SRRT / ARS2 Goat anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
SRRT / ARS2 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa627-876) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
SRRT / ARS2 Antibody - Detection of mouse ARS2 by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti- ARS2 used at a dilution of 1:5,000 (0.2µg/ml). Detection: DAB
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa826-876) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa54-81) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa54-81) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa54-81) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa54-81) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa54-81) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa54-81) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
SRRT / ARS2 Antibody - WB on mouse tissue lysate. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:1000 incubated at 4°C overnight.
Select
SRRT / ARS2 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$393
SRRT / ARS2 Antibody - Detection of human and mouse ARS2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ARS2 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SRRT / ARS2 Antibody - All lanes: Anti-srrt Antibody (C-Term) at 1:2000 dilution. Lane 1: HeLa whole cell lysates. Lane 2: Jurkat whole cell lysates. Lane 3: NIH/3T3 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 103 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
SRRT / ARS2 Rabbit anti-Zebrafish Polyclonal (aa878-910) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
SRRT / ARS2 Antibody - All lanes: Anti-srrt Antibody (C-Term) at 1:2000 dilution. Lane 1: Zebrafish muscle lysates. Lane 2: Zebrafish lysates. Lane 3: Jurkat whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 103 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
SRRT / ARS2 Rabbit anti-Zebrafish Polyclonal (aa733-766) Antibody
Zebrafish, Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
SRRT / ARS2 Antibody - SRRT Antibody western blot of 293 cell line lysates (35 ug/lane). The SRRT antibody detected the SRRT protein (arrow).
Select
SRRT / ARS2 Rabbit anti-Human Polyclonal (aa54-81) Antibody
Human
WB
Unconjugated
400 µl/$393
SRRT / ARS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
100.5 kDa
100 µg/$710
SRRT / ARS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
100.5 kDa
20 µg/$215
SRRT / ARS2 Protein - 12.5% SDS-PAGE of human ARS2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
72.82 kDa
2 µg/$439
SRRT / ARS2 Protein - Purified recombinant protein SRRT was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
100.5 kDa
20 µg/$1,107
SRRT / ARS2 Protein
Select
Sf9 Cells
DDK,C-terminus
100.5 kDa
20 µg/$677
Viewing 1-20 of 20 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).