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| Catalog Number | Size | Price |
|---|---|---|
| LS-C344019-10 | 10 µg | $318 |
| LS-C344019-100 | 100 µg (0.5 mg/ml) | $470 |
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Polyclonal Rabbit anti‑Human SIRT2 / Sirtuin 2 Antibody (aa165‑187, IHC, WB) LS‑C344019
Polyclonal Rabbit anti‑Human SIRT2 / Sirtuin 2 Antibody (aa165‑187, IHC, WB) LS‑C344019
Note: This antibody replaces LS-C389204
Antibody:
SIRT2 / Sirtuin 2 Rabbit anti-Human Polyclonal (aa165-187) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Chimpanzee, Orangutan, Monkey, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
SIRT2 / Sirtuin 2 Rabbit anti-Human Polyclonal (aa165-187) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Chimpanzee, Orangutan, Monkey, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Sirtuin 2 antibody LS-C344019 is an unconjugated rabbit polyclonal antibody to Sirtuin 2 (SIRT2) (aa165-187) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB.
Target
Human SIRT2 / Sirtuin 2
Synonyms
SIRT2 | SIR2 | Sir2-related protein type 2 | SIR2L | SIR2L2 | Sirtuin 2 | Silent information regulator 2 | SIR2-like protein 2 | Sirtuin type 2
Host
Rabbit
Reactivity
Human, Chimpanzee, Orangutan, Monkey, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Modifications
Unmodified
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human SIRT2(165-187 aa YTQNIDTLERIAGLEQEDLVEAH), different from the related mouse and rat sequences by three amino acids.
Epitope
aa165-187
Specificity
Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network. .
Applications
- IHC
- IHC - Paraffin
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg sodium azide.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500µg/ml.
Storage
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SIRT2 / Sirtuin 2
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Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse
Applications:
Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
