Target
Human SFRP-3 / FRZB
Synonyms
FRZB | FRZB-1 | FIZ | FRE | FRITZ | Fritz and frizzled | Frizzled homolog-related | FRP-3 | FRZB-PEN | HFIZ | FRP | FZRB | SFRP-3 | SRFP3 | OS1 | Frezzled | Frizzled related protein 3 | Frizzled-related protein | Frizzled-related protein 1 | FRZB1 | SFRP3
Reactivity
Human
(tested or 100% immunogen sequence identity)
Purification
Immunogen affinity purified
Immunogen
E.coli-derived human FRZB recombinant protein (Position: E176-N325). Human FRZB shares 90% amino acid (aa) sequence identity with mouse FRZB.
Specificity
Expressed primarily in the cartilaginous cores of the long bone during embryonic and fetal development and in the appendicular skeleton (6-13 weeks). At 13 weeks of gestation, transcripts were present in early chondroblasts of the tarsal bones of the foot, the carpal bones of the hands and the epiphysis of long bones. Highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. Weakly expressed in lung and liver.