Human SCGB2A2 / Mammaglobin A

Rabbit

Human (tested or 100% immunogen sequence identity)

Monoclonal

Unconjugated

Unmodified

C-Terminus 16 aa peptide sequence of human mammaglobin coupled to KLH as a carrier protein

• IHC (1:50)
• Western blot (1:50)
• ELISA (1:50)

Formalin-fixed tissue may be pre-treated for 30 minutes at 100°C with antigen retrieval, preferably in a pressure cooker. Detection of mammaglobin in metastatic mamma carcinoma, differential diagnosis of metastases in sentinel lymph nodes Mammaglobin A is a breast gland associated glycoprotein, distantly related to the secretoglobin family including human Uteroglobin and Lipophilins. Unlike other secretoglobin family members Mammaglobin mRNA seems to be Mamma-specific (exception skin). Mammaglobin has been detected by immunohistochemical approach in intact breast tissue as well as in adenocarcinoma. It seems to be up-regulated in cancer tissues. The monoclonal antibody is suitable for the detection of occult mamma carcinoma cells in sentinel lymph nodes and in peripheral blood. The overall sensitivity of mammaglobin detection on paraffin sections of mamma carcinoma was reported to be >80% (Fanger et al. 2002; Han et al. 2003). 10 KDa Mammaglobin from human breast tissue, no cross-reactivity with mammaglobin B, lipophilin and uteroglobin.

PBS, 0.09% Sodium Azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q13296 NCBI: NM_002411 NP_002402.1