Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Gene Name: | Ras and Rab interactor 1 |
Synonyms: | RIN1, Ras and Rab interactor 1, Ras inhibitor JC99, Ras inhibitor 1, Ras inhibitor RIN1 |
Target Sequences: | NM_004292 NP_004283.2 Q13671 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.