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| Catalog Number | Size | Price |
|---|---|---|
| LS-C501626-50 | 50 µg | $294 |
| LS-C501626-100 | 100 µg | $360 |
Polyclonal Rabbit anti‑Human RBBP8 / CTIP Antibody (FITC) LS‑C501626
Polyclonal Rabbit anti‑Human RBBP8 / CTIP Antibody (FITC) LS‑C501626
Antibody:
RBBP8 / CTIP Rabbit anti-Human Polyclonal (FITC) Antibody
Application:
ELISA
Reactivity:
Human
Format:
FITC, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
RBBP8 / CTIP Rabbit anti-Human Polyclonal (FITC) Antibody
Application:
ELISA
Reactivity:
Human
Format:
FITC, Unmodified
Other formats:
Specifications
Description
CTIP antibody LS-C501626 is an FITC-conjugated rabbit polyclonal antibody to human CTIP (RBBP8). Validated for ELISA.
Target
Human RBBP8 / CTIP
Synonyms
RBBP8 | CTIP | DNA endonuclease RBBP8 | RIM | SAE2 | COM1 | CtBP-interacting protein | JWDS | RBBP-8 | SCKL2 | Seckel syndrome 2
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human DNA endonuclease RBBP8 protein (126-331AA)
Specificity
Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.
Applications
- ELISA
- Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About RBBP8 / CTIP
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To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 2/12/2025
Date Requested: 2/12/2025
