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Catalog Number Size Price
LS-C500916-50 50 µg $294 
LS-C500916-100 100 µg $360 
PTCH1 / Patched 1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using PTCH1 Antibody at dilution of 1:100
PTCH1 / Patched 1 Antibody - Immunofluorescent analysis of HepG2 cells using PTCH1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PTCH1 / Patched 1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using PTCH1 Antibody at dilution of 1:100
PTCH1 / Patched 1 Antibody - Immunofluorescent analysis of HepG2 cells using PTCH1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Polyclonal Rabbit anti‑Human PTCH1 / Patched 1 Antibody (IHC, IF) LS‑C500916

Polyclonal Rabbit anti‑Human PTCH1 / Patched 1 Antibody (IHC, IF) LS‑C500916

Antibody:
PTCH1 / Patched 1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IF, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$294
LS-C500916-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
PTCH1 / Patched 1 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IF, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Patched 1 antibody LS-C500916 is an unconjugated rabbit polyclonal antibody to human Patched 1 (PTCH1). Validated for ELISA, IF and IHC.
Target
Human PTCH1 / Patched 1
Synonyms
PTCH1 | NBCCS | Patched 1 | Patched homolog 1 | Protein patched homolog 1 | PTC1 | PTCH | PTCH protein +12b | PTCH protein -10 | PTCH protein -3,4,5 | Patched | Patched protein homolog 1 | BCNS | HPE7 | Patched homolog | PTC | PTCH protein +4 | PTCH11
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with FITC, Biotin, HRP.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Protein patched homolog 1 protein (1180-1411AA)
Specificity
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Applications
  • IHC
  • Immunofluorescence
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PTCH1 / Patched 1
Q13635 NM_000264 NP_000255.2

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Requested From: United States
Date Requested: 11/22/2024