Target
Pig PDYN / ProDynorphin
Synonyms
PDYN | ADCA | Beta-neoendorphin-dynorphin | Leumorphin | Preprodynorphin | Spinocerebellar ataxia 23 | PENKB | Prodynorphin | Rimorphin | SCA23 | Leu-enkephalin | Preproenkephalin B | Proenkephalin-B
Reactivity
Pig, Human, Monkey, Rat
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Immunogen
Synthetic peptide, Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln corresponding to aa1-17 of porcine Dynorphin A.
Specificity
Recognizes porcine Dynorphin A. Blocks with dynorphin 1-17 and 1-8. Does not block other related peptides. Cells are found in the paraventricular and supraoptic nucleus. Fibers are found in the lateral hypothalamus in rat brain of 4% FA perfused colchicine tissue. Species cross-reactivity: monkey, rat, Rhesus monkey and human.
Applications
- IHC
- IHC - Paraffin
- IHC - Frozen
- Radioimmunoassay (1:15000)
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Usage
Suitable for use in Immunohistochemistry and Radioimmunoassays. Immunohistochemistry (frozen): 1:50-1:1250. Immunohistochemistry: Paraffin sections require antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer, pH 6.0 is recommended. Overnight incubation is recommended. Radioimmunoassay: 1:15000.
Presentation
PBS, 0.09% sodium azide, 0.1% BSA, 40% glycerol.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PDYN / ProDynorphin